Ilosone
Drug Info
Ilosone
Drug Uses : Erythromycin ( Ilosone )
is a macrolide antibiotic which has an antimicrobial spectrum similar to or slightly wider than that of penicillin, and is often used for people who have an allergy to penicillins. For respiratory tract infections, it has better coverage of atypical organisms, including mycoplasma and Legionellosis. It is also used to treat outbreaks of chlamydia, syphilis, acne and gonorrhea. Structurally, this macrocyclic compound contains a 14-membered lactone ring with ten asymmetric centers and two sugars (L-cladinose and D-desoamine), making it a compound very difficult to produce via synthetic methods.
How to Use
Ilosone
: This medication may be taken with food or milk if stomach upset occurs. Antibiotics work best when the amount of medicine in your body is kept at a constant level. Do this by taking the medication at evenly spaced intervals throughout the day and night. Continue to take this medication until the full prescribed amount is finished even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow resulting in a relapse of the infection. Inform your doctor if your condition persists or worsens.
Ilosone
Precautions: Tell your doctor your medical history, especially of: liver disease/jaundice, allergies (especially drug allergies). Use of this medication for prolonged or repeated periods may result in a secondary infection (e.g., oral, bladder or vaginal yeast infection) Caution is advised when this drug is used in infants. Though very unlikely to happen, a stomach problem called IHPS (infantile hypertrophic pyloric stenosis) has been noted. Contact your child's doctor immediately if the child has persistent vomiting or increased irritability. This drug should be used only if clearly needed during pregnancy. Small amounts of drug do appear in breast milk, so consult your doctor before breast-feeding.
Ilosone
Drug Interactions: Tell your doctor of all the drugs you may use (prescription and nonprescription), especially of the following: carbamazepine, cyclosporine, theophylline, certain benzodiazepines (e.g., midazolam, triazolam), warfarin, felodipine (a calcium channel blocker), cisapride, corticosteroids (e.g., prednisone), digoxin, ergotamine-containing medications, sildenafil, certain live vaccines, disopyramide, phenytoin, all other antibiotics, certain "statin" drugs used to treat high cholesterol (e.g., atorvastatin, lovastatin, simvastatin). Other drugs besides erythromycin which may affect the heart rhythm (QTc prolongation in the EKG) include dofetilide, pimozide, quinidine, sotalol, procainamide, and sparfloxacin among others. QTc prolongation can infrequently result in serious, rarely fatal, irregular heartbeats. Consult your doctor or pharmacist for details. Ask for instructions about whether you need to stop any other QTc-prolonging drugs you may be using in order to minimize the risk of this effect. This drug may interfere with the effectiveness of birth control pills. Discuss using other methods of birth control with your doctor. Do not start or stop any medicine without doctor or pharmacist approval.
Ilosone
Possible Side Effects: Erythromycin inhibits the cytochrome P450 system, particularly CYP3A4, which can cause it to affect the metabolism of many different drugs. If CYP3A4 substrates such as simvastatin (Zocor), lovastatin (Mevacor) or atorvastatin (Lipitor) are taken concomitantly with erythromycin, levels of the substrates will increase, often causing adverse effects. A noted drug interaction involves erythromycin and simvastatin, resulting in increased simvastatin levels and the potential for rhabdomyolysis.
Gastrointestinal disturbances such as diarrhea, nausea, abdominal pain and vomiting are fairly common so it tends not to be prescribed as a first-line drug. However, erythromycin may be useful in treating gastroparesis due to this pro-motility effect. Intravenous erythromycin may also be used in endoscopy as an adjunct to clear gastric contents. More serious side-effects, such as arrhythmia, reversible deafness are rare. Allergic reactions, while uncommon, may occur, ranging from urticaria to anaphylaxis. Cholestasis, Stevens-Johnson syndrome and toxic epidermal necrolysis are some other rare side effects that may occur. Erythromycin has been shown to increase the probability of pyloric stenosis in children whose mothers took the drug during the late stages of pregnancy or while nursing.
Ilosone
Overdose: Seek emergency medical attention immediately if an overdose is suspected. Symptoms of
Ilosone
overdose include: dizziness or drowsiness, fainting, nausea, vomiting, facial flushing, fast heartbeat, and loss of consciousness.
Ilosone
Storage: Store
Ilosone
at room temperature away from moisture and sunlight. Avoid excessive heat. Avoid freezing. Keep out of the reach of children. Dispense of this medicine in a tight, light-resistant container. Do not store
Ilosone
in the bathroom.
Ilosone
Missed Dose: Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.
Disclaimer: The information found on this website is for informational purposes only. It does not cover all possible uses, procedures, safety measures, side effects, or drug interactions of the products. We are not responsible for the accuracy and reliability of this drug information, or any consequences arising from the use of this information. This is only general information and should not be relied on for any purpose. |
